Diabetic patients with Aspergillus fumigatus infection need to actively apply voriconazole and other antifungal drugs for treatment in addition to hypoglycemic treatment. Diabetic patients infected with Aspergillus fumigatus first need to treat the underlying disease, i.e., control of blood glucose, and then need to apply voriconazole, itraconazole, posaconazole and other antifungal drugs for antifungal treatment. In case of failure of monotherapy, intolerance, multi-site infection, etc., a combination of drugs, such as voriconazole combined with echinocandins, can be administered. After the occurrence of Aspergillus fumigatus infection in diabetic patients, it is necessary to combine with their own conditions under the guidance of the doctor to standardize the treatment.