A high activated partial thromboplastin time is not necessarily abnormal; when its time exceeds 10 seconds or more, it indicates a high risk of bleeding. The abbreviation for activated partial thromboplastin time is APTT and is an important indicator in coagulation tests that reflects the normal function of various endogenous coagulation pathways. If the APTT is under 10 seconds, it may be related to a prolonged partial thromboplastin time caused by the patient’s blood draw or other reasons, not necessarily a pathological cause, and requires retesting. If the activated partial thromboplastin is elevated for more than 10 seconds, it indicates a high risk of bleeding and it is recommended that supplemental coagulation factors should be given; at the same time, the cause of the elevated activated partial thromboplastin should be actively sought and the cause of the elevated activated partial thromboplastin should be clarified and treated accordingly. In addition, patients with high activated partial thromboplastin time should also avoid trauma, which may cause massive bleeding, and should seek early diagnosis and treatment at the hematology department to avoid delaying the disease.