I often encounter some patients, facial dermatitis and other pruritic diseases, to buy some drugs to buy their own pharmacy topical application, or even self-application of hormone cream. These patients will say that the efficacy is not bad, and they will get better after a few times. Therefore, every time a similar situation occurs on the face, they will repeatedly use the self-purchased medication and use it when they think of it, but not when they forget it, or not when the symptoms get better, and then use it several times when it gets worse. In the end, some patients will find that the frequency of facial skin allergy is increasing, becoming more and more sensitive, the skin is flushed, and even cannot withstand the stimulation of hot and cold changes, and some faces begin to appear red blood, etc. These may be due to the fact that the drugs used contain hormones. These may be the adverse reactions caused by the drugs used containing hormones and the long-term irregular use of drugs. Therefore, it is necessary to remind patients: 1, facial topical drugs should be selected strictly and very carefully. 2, self-purchased drugs to choose the drug licensed drugs are relatively safe. 3, the application of hormonal drugs, it is best to apply under the guidance of a specialist. Because there are weak, medium and strong glucocorticoid potencies, and there are strict requirements for the types of application in different parts of the body, inappropriate long-term use can lead to skin atrophy, hirsutism, vasodilation, hormone dependence and other side effects.