Cirrhosis is a chronic liver disease that develops gradually from a variety of chronic hepatitis, and if left unchecked has the potential to develop a range of complications. Stem cell transplantation, a relatively new modality, has also shown some efficacy in the treatment of cirrhosis. Stem cell transplantation is mainly done through the patient’s own stem cells, which are cultured and reintroduced into the liver to form new liver cells locally to regenerate and replace the liver cells that have been destroyed, helping to restore liver function to the greatest extent possible. It can reverse cirrhosis and facilitate the repair of the disease, and can be a better treatment modality among cirrhotic patients. If this effect does not work, it is better to be treated by liver transplantation.