Diabetic foot co-infections often present with a foul odor and are treated with aggressive blood sugar control, debridement, antibiotics, and amputation. For patients with diabetic foot, once the infection is diagnosed, it is important to actively apply broad-spectrum antibiotic therapy, including amoxicillin and cephalosporin, while waiting for bacterial culture. Patients with diabetic foot need surgical debridement to remove necrotic tissue and local wound care such as preventing the ulcer site from aggravating; they also need to actively control their blood glucose, and if there is still no improvement they need to reevaluate antibiotics or take surgical amputation. The most important thing is to prevent the occurrence of diabetic foot, when diabetic foot needs to be timely to the front of the regular hospital, active control of blood glucose, under the guidance of professional doctors to take appropriate treatment measures to improve the quality of life.