Splenectomy will be performed in patients with cirrhosis combined with hypersplenism, splenomegaly, and upper gastrointestinal bleeding. Hypersplenism is manifested by a decrease in blood counts in routine blood work, including a decrease in white blood cell count, red blood cell count, and platelet count, and in some patients is accompanied by symptoms of liver insufficiency. Splenectomy can be performed for simple hypersplenism, or splenectomy with peripancreatic vascular dissection if the patient has upper gastrointestinal bleeding or if gastroscopy indicates severe varices in the esophagogastric fundic veins. Some existing clinical studies have confirmed that splenectomy in patients with cirrhosis with hypersplenism can improve the patient’s liver function to some extent and improve the long-term prognosis.