In patients with hyperbilirubinemia, if the bilirubin is high, the urine will show an orange-yellow color and a teal color. For patients with hyperbilirubinemia, the first step is to check the liver function to see if the total bilirubin is above 34.2 umol/L. If the elevated total bilirubin is mainly direct bilirubin, the patient is likely to have an elevated urine. If the elevated total bilirubin is mainly due to direct bilirubin, the patient should be considered to have biliary obstruction, and if there is a combination of alkaline phosphatase and GGT elevation, more often than not, the patient should consider whether there is stone formation in the biliary tract. In this case, it is recommended to further investigate the ultrasound of the upper abdomen or MRCP water imaging of the biliary tract. Through these examinations, we can identify whether the obstruction in the biliary tract is caused by stones, tumor disease of the biliary tract, or the occupancy of the head of the pancreas that compresses the bile ducts, and provide different treatments according to different causes. Stones in the bile ducts can be cured after lithotripsy under ERCP. In addition, in some patients with hepatocellular jaundice, total bilirubin and indirect bilirubin may be elevated. In this case, the patient needs to be further investigated for hepatitis B and hepatitis C antibodies to see if the patient has the possibility of hepatitis and whether the patient has autoimmune hepatitis, which causes jaundice after hepatocyte necrosis.