Blisters on the back of the feet from boiling water can lead to venous thrombosis. When the back of the feet by boiling water blisters will cause the body’s stress response, resulting in a large number of clotting factors and platelet aggregation may form a thrombus. The patient may appear local redness, heat, swelling, a few patients will appear temperature rise, in the subcutaneous tissue weaker parts of the palpable stripes like hard knots and so on. Prolonged bed rest and sedentary behavior after burns on the instep may also lead to venous thrombosis. It is recommended that the patient is scalded to timely medical examination, according to the condition of targeted treatment, while patients should also pay attention to the affected area of the care and protection, do not massage the affected limbs, to prevent trauma, to avoid causing thrombus dislodgement, triggering serious pulmonary embolism, and so on.