Neonatal hypoglycemia is clinically diagnosed in newborns with blood glucose below 2.2 mmol/L. Blood glucose below 2.6 mmol/L requires prompt treatment with oral or intravenous push of glucose and blood glucose monitoring again after half an hour. Hypoglycemia must be treated promptly, because hypoglycemia can be manifested as poor response, poor milk eating, drowsiness in the near future, bruising and neonatal convulsions can occur in serious cases, and even hypoglycemic encephalopathy can occur; intellectual, motor and hearing impairment is left in the far future. Neonatal hypoglycemia can be divided into transient hypoglycemia and uncorrectable hypoglycemia. Transient hypoglycemia is mostly caused by maternal gestational diabetes, where the fetus leaves the mother’s sugar supply interrupted and the insulin level is still relatively high, and uncorrectable hypoglycemia is mostly caused by pancreatic diseases.