Whether neonatal hypoglycemia can be cured is closely related to the cause of the disease and whether there is brain damage. If neonatal hypoglycemia is caused by a delay in breastfeeding, it can be cured after treatment. Some genetic metabolic diseases or brain damage require long-term treatment. Temporary hypoglycemia in newborns is caused by delayed breastfeeding, insufficient glucose intake, asphyxia, neonatal sclerosis, and other serious illnesses. This type of hypoglycemia can be cured by glucose supplementation and treatment of the primary disease. Some inherited metabolic diseases such as neonatal galactosemia and glycogen storage disease, and endocrine diseases such as congenital pituitary hypoplasia and growth hormone deficiency, etc. Hypoglycemia caused by these diseases requires long-term treatment, and whether it can be cured or not is also related to the primary disease. Some children can be well cured of hypoglycemia after controlling the disease, while some children with difficult-to-cure diseases will have recurrent hypoglycemia. Regardless of the etiology, frequent and repeated hypoglycemia, with or without symptoms, can cause brain cell damage, often leaving sequelae such as intellectual disability, motor disability, and dysfunction, requiring long-term treatment. Once hypoglycemia occurs in newborns, it is necessary to seek medical treatment in time to avoid damage to the baby’s brain cells.