Coronary artery bypass grafting (CABG), commonly known as coronary artery bypass grafting, is currently one of the main treatments for coronary atherosclerotic heart disease. The materials used for bypass include the internal mammary artery, saphenous vein, radial artery, small saphenous vein, gastroretinal artery and other body’s own blood vessels, of which the first three are the most commonly used. Currently, there are two types of surgical procedures classified according to whether or not extracorporeal circulation is used: On-Pump CABG and Off-Pump CABG, both of which have their own advantages, disadvantages and indications, and the academic debate between them has never stopped and will continue. It combines the advantages of minimally invasive medical intervention with the efficacy of surgical bypass for long-term patency of the internal mammary artery, and it is believed that more patients will be treated with this technique in the future. The postoperative treatment of coronary artery disease is very important, no less than the surgery itself. Since coronary heart disease is a metabolic disease of internal medicine, surgery is not a radical cure, but merely relieves the ischemia of the heart, and long-term postoperative medical drug treatment cannot be neglected. Among the many pharmacological treatments, statins, aspirin and beta-blockers are the three most important ones.