Azithromycin and cefixime can both be used to treat patients with bronchitis caused by some susceptible bacteria, and no one treatment is better than the other, as each person is infected with a different type of bacterial flora and a different susceptibility to the drug, and the effectiveness of the treatment is also different. It is important to note that most bronchitis is not a bacterial infection, and antibacterial drugs are not used unless there is a clear bacterial infection. Bronchitis is mainly due to microbial infections, physical or chemical stimuli, of which viral infections are the most common, but also bacterial infections, mainly manifested as coughing and coughing up phlegm. It is usually treated with symptomatic treatment such as cough suppressant, phlegm dissolution, asthma, etc. Most of them do not need antimicrobial treatment unless there is a clear bacterial infection. Azithromycin belongs to the class of macrolide antimicrobial drugs, suitable for the treatment of specific microorganisms caused by mild to moderate bronchitis, pneumonia and other diseases of the treatment, such as Haemophilus influenzae, Catamorium, Streptococcus pneumoniae, Mycoplasma pneumoniae / Chlamydia, etc.; the drug may cause diarrhea, nausea, abdominal pain, rash and other adverse reactions, is prohibited in the person who has an allergic reaction to macrolides and those who have hepatic insufficiency. Cefixime is a third-generation cephalosporin effective in patients with bronchitis caused by bacteria such as Streptococcus (except Enterococcus), Pneumococcus, Gonococcus, Escherichia coli, Klebsiella and Influenza bacteria. There may be adverse reactions such as diarrhea, rash, blood disorders, renal dysfunction, etc. after using this product, and it is prohibited for those who are allergic to cephalosporin. When bronchitis occurs, it is necessary to consult the hospital in time to identify the cause of the disease and carry out targeted treatment to avoid delaying the condition. The above drugs should be used under the guidance of a physician.