Calcification of the prostate is one of the common prostate lesions in men, mostly occurring between the ages of 40 and 60. The so-called calcification, which pathologically refers to the deposition of calcium salts in the local tissue, can be a normal physiological process or can be seen in certain pathological conditions. Because of the lack of typical clinical symptoms and signs, prostate calcification is mostly detected by imaging during the examination of prostate disease and other diseases of the urinary system. In imaging, prostate calcification appears as strong echogenic foci or high-density foci in the prostate. With the popularization and improvement of ultrasound technology, the detection rate of prostate calcification has increased significantly. The calcification of the prostate should be distinguished from prostate stones. The actual calcification of the prostate is a real stone formed in the prostate duct and in the prostate alveoli of the patient. These stones are as small as a grain of rice and can be round or oval in shape with a hard texture. However, current medical imaging techniques are difficult to distinguish between calcified foci in the prostate alveoli or ducts (true stones) and in the stroma (pseudoliths). Therefore, most scholars now agree that strong echogenic foci or high-density foci in the prostate are collectively referred to as prostatic calcification in imaging. Etiology When dilatation of the prostatic ducts and alveoli occurs for a variety of reasons or when prostatic fluid accumulates, it can cause the shedding of epithelial cells to collect with amyloid vesicles (prostatic coagulum) and secretions in the cystic cavity, which can form calcifications if there is a gradual deposition of calcium salts. The chemical prostatitis due to urinary reflux is more likely to cause calcification formation. The cause of calcification of the prostate is still unclear and may be related to degenerative changes in the prostate tissue, chronic prostatitis, retention of prostate fluid, frequent congestion of the prostate, narrowing of the prostate ducts, disorders of calcium and phosphorus metabolism and psychosocial factors. It is generally believed that calcification is closely related to prostatitis for those aged <40 years and to prostate enlargement for those aged >40 years. 1, the existing research shows that the presence of nano-bacterial infection in the prostate may lead to the occurrence of prostate calcification, while prostate calcification may cause prostatitis to be difficult to treat and easy to recur. The exact relationship between the three needs to be confirmed by further relevant studies. The actual fact is that the actual calcification of the prostate itself has no obvious signs and symptoms, but it is mostly discovered during the examination of prostate disease and other diseases of the urinary system by imaging. The actual fact that ultrasound is easy to operate, non-invasive and reproducible is the preferred method of clinical diagnosis of prostate calcification. 4, Diagnosis If there is a history of prostate disease (such as prostate hyperplasia, inflammation, tuberculosis, tumor), and strong echogenic foci or high-density foci are found in the prostate by ultrasound, X-ray or CT, the diagnosis of prostate calcification can be made. 5, Differential diagnosis should pay attention to differentiate from calcification of prostate tumor, tuberculosis calcification, bladder stones, posterior urethral stones, seminal vesicle stones, etc. 6, treatment for calcification of the prostate without obvious clinical symptoms, generally do not need to be treated. If there are other prostate lesions, treatment will be given according to the specific situation. 7, prevention to maintain a good mood, cultivate hobbies, build tenacious confidence, eliminate anxiety and divert attention from prostate disease. 8, diet attention, avoid spicy food, eat more fruits and vegetables, and develop good habits. 9, pay attention to the combination of work and rest, to prevent excessive fatigue, appropriate physical exercise, especially to strengthen the pelvic muscles, forbid long-term sedentary, cycling, etc. 10, sexual life should be regular, avoid too little and too often.