Spring is the season for young girls to show their graceful figures and colorful clothes, and it is also the time for more obese patients in endocrine clinics, because it is the season for fat people to suffer. However, each obese patient has his or her own characteristics, so we can’t lose weight in a uniform way. First of all, we have to exclude secondary obesity, then we have to find out the cause of obesity and determine whether treatment is needed. For endocrinologists, we often divide patients into white, yellow, black and red fat according to their skin color, followed by benign obesity and malignant obesity according to whether they have abnormal metabolism. White obesity is often obese since childhood and familial obesity, fat is mostly uniformly distributed, moving freely and without obvious metabolic abnormalities such as increase in blood pressure, blood sugar and blood lipids, which mostly do not need excessive attention and treatment, but sometimes excessive obesity will cause sex hormone changes, such as male feminization and breast development, and women will also have various endocrine problems, which also need to be treated with intervention. And black fat is often represented mainly by acanthosis nigricans, which is manifested as skin pigmentation on the neck and underarms, giving a feeling of unwashed skin, often as a skin manifestation of insulin resistance, mostly accompanied by fatty liver, abnormal glucose metabolism, delayed sexual development, menstrual disorders and other problems, so it needs active treatment. And yellow fat to endocrine metabolic changes such as hypothyroidism as the representative, often manifested as hair thinning, weak pulse, lethargy, chest tightness and shortness of breath and other problems, need to supplement the corresponding hormone deficiency and remove the cause of obesity. And the spirit glowing, easily excited red fat is also not a good phenomenon, often due to abnormal cortisol increase, sometimes due to obesity, and sometimes due to pituitary and adrenal gland diseases and drugs, often manifested as full moon face, purple skin lines, increased hair, blood pressure, etc., also need active treatment. So obesity is a disease, weight loss is a medical practice, do not do it at will, blindly believe in exaggerated in fact weight loss products and drugs publicity, will bring more serious consequences due to weight loss, such as some women in the process of weight loss appeared menopause, heart problems, gastrointestinal symptoms, psychiatric symptoms and sleep disorders, etc., are not scientific methods caused.