1. It is generally believed that the treatment effect of infertility is unsatisfactory, mainly due to the following reasons: (1) In the past, the basic research on this disease, especially on male infertility, lagged far behind the clinical needs. (2) Infertility is a common result of various causes, and its causes are very complex, with many of them being unclear. (3) Lack of professional staff for diagnosis and treatment of infertility and corresponding specialties, infertility patients are transferred to obstetrics and gynecology, urology, endocrinology and other departments, and the diagnosis of infertility varies, and the effect of its treatment can be imagined. (4) Various kinds of charlatans with ancestral recipes, palace secret recipe banner, its treatment effect is close to zero. 2. In recent years, the treatment effect of infertility has been significantly improved, mainly due to: (1) the basic research on infertility, especially the research on male infertility has made certain progress. (2) Interdisciplinary infertility treatment centers have been set up and specialized physicians in infertility diagnosis and treatment have been trained. (3) New methods of infertility treatment have been explored, such as improved artificial insemination, in vitro fertilization, and sperm microinjection. According to foreign reports, more than half of the infertile couples who seek treatment get pregnant.