Patients with intracranial infection after neurosurgery usually have an incubation period of 3-7 days after surgery. Once symptoms such as fever, headache, nausea, vomiting and possibly even coma appear 3-7 days after surgery, it is important to suspect the occurrence of intracranial infection at this time. In addition to the clinical symptoms mentioned above, the patient’s physical signs should also be checked. If there is an intracranial infection, there may be positive meningeal irritation signs, as well as blood indicators, such as the examination of routine blood leukocytes will increase, and when the cerebrospinal fluid examination is done, the patient’s cerebrospinal fluid may be cloudy in appearance or may be purulent, and the white blood cells are high, the protein content is high and the sugar content is low. intracranial infection is more well founded. In patients with intracranial infections, intracranial infections are more likely to occur in the early postoperative period with positive bacteria, so anti-positive drugs will be chosen for treatment.