Chest tightness, shortness of breath, lying down to sleep all right, most of them consider the respiratory system related diseases caused by, including chronic obstructive pulmonary disease, pleural effusion, cardiovascular diseases and other diseases, as follows: 1, chronic obstructive pulmonary disease and pleural effusion and other diseases: in lying down to rest, especially in the case of the affected side lying position, can make the symptoms improve; 2, cardiovascular system diseases: such as variant angina, cardiac insufficiency caused by, when lying down to rest often makes the symptoms of cardiac insufficiency aggravated, myocardial ischemia aggravated and the corresponding symptoms, including chest tightness, chest pain and paroxysmal dyspnea at night, and even telangiectatic breathing, acute pulmonary edema and other situations. Therefore, for chest tightness and shortness of breath, chest imaging is recommended to clarify the presence or absence of respiratory diseases, blood gas analysis is recommended to clarify the presence or absence of respiratory failure, and systematic treatment such as antibiotics, expectoration and wheezing is given.