Myocardial bridge is a congenital disease, mainly due to coronary vessels traveling into the myocardium and compressing the coronary arteries during myocardial contraction, causing myocardial ischemia. Generally there are no drugs that can treat structural abnormalities, but patients with myocardial bridges can take drugs such as beta-blockers, or non-dihydropyridine calcium antagonists under the guidance of a doctor, which can effectively improve the symptoms of myocardial bridges. Patients with myocardial bridges mainly take drugs that slow down the heart rate and reduce myocardial oxygen consumption, such as beta-blockers, including metoprolol tartrate and bisoprolol fumarate, which can effectively reduce heart conduction and slow down the heart rate, as well as reduce myocardial oxygen consumption. For patients who are allergic to these drugs, non-dihydropyridine calcium antagonists, such as diltiazem and verapamil, can be chosen to help control the patient’s heart rate and reduce myocardial oxygen consumption. If the patient still has typical clinical symptoms with substandard heart rate control after taking a single of these drugs, a combination of both types of drug therapy can be considered to reduce the degree of myocardial ischemia and reduce the incidence of angina pectoris. Usually, the compression of the myocardial bridge is not particularly heavy and the patient will not have obvious symptoms in the short term. However, when patients are emotionally excited, overworked or strenuously active, which leads to an increase in myocardial oxygen demand, it may make the compression of the myocardial bundle on the blood vessels heavier, thus causing an increase in myocardial ischemia and inducing the occurrence of angina pectoris. Therefore, in addition to medication, myocardial bridges should also pay attention to lifestyle adjustments, avoiding strenuous activities, overexertion and excessive emotional fluctuations.