High blood uric acid with gout manifests itself differently in different periods, which is categorized into asymptomatic period, acute arthritis period, gout stone and chronic arthritis period. 1. Asymptomatic period: only hyperuricemia, but no obvious joint swelling, pain and other clinical manifestations, some patients can be lifelong without symptoms. 2. Acute arthritis stage: severe joint pain often occurs at midnight or early in the morning, with redness, swelling, heat, pain and dysfunction of the joints, and pain is common in the first metatarsophalangeal joint. The pain is common in the first metatarsophalangeal joint. The pain will be relieved on its own in some patients. 3. Gout stone and chronic arthritis stage: gout stones are common in the auricle, around the joints, hawksbill, patella and other places. Patients without standardized treatment will develop chronic arthritis, with swelling and pain in the affected joints. If the above symptoms occur, it is recommended to consult a regular hospital in time and standardize the treatment under the guidance of a doctor to avoid serious complications.