Blisters on the inside of the tongue are not necessarily a symptom of AIDS, but may be a result of fire or inflammation of the mouth. AIDS is divided into acute phase, asymptomatic phase and AIDS disease phase according to the specific course of the disease. In the acute stage, there will be fever, headache, nausea, vomiting, diarrhea, muscle pain, joint pain, etc. There may be some redness, swelling and congestion in the mouth. In the asymptomatic phase, there is no clinical manifestation. During the AIDS phase, because the immune system is severely depressed, it is possible to develop oral candidiasis infection, which is manifested by a lot of white powdery substance attached to the tongue. Other oral herpes simplex virus infections may also occur, which may manifest as blisters on the lips or tongue.