The drugs of choice for controlling malaria episodes are chloroquine, artemisinin-based drugs and quinine. The first-line treatment regimen should take into account local guidelines, drug sensitivity patterns and the availability of appropriate drugs. Plasmodium falciparum may or may not be sensitive to chloroquine, as determined by local antimalarial resistance data. 1. Chloroquine: The main control drug for malaria attacks, it has a curative effect on P. falciparum malaria and is currently used with good and widely recognized clinical efficacy in the treatment of malaria. Chloroquine may bring blurred vision, skin allergic reactions and other adverse reactions, so people with fundus lesions should be cautious. 2. Artemisinin-based drugs: artesunate, can be used to control malaria, malaria, malaria, etc. It has a strong killing effect on malaria parasites, and it is absorbed rapidly after using the drug. However, adverse reactions such as abdominal pain, nausea, vomiting and diarrhea may occur after use, and pregnant and lactating women should be cautious. 3. Quinine: It is suitable for controlling the attack of falciparum malaria such as cerebral falciparum malaria. Nausea and vomiting, dizziness and nausea, hearing loss, temporary deafness, labor induction and other adverse reactions may occur after taking the drug, pregnant and lactating women are prohibited. The specific use of drugs to control malaria attacks should be decided by a doctor, malaria patients should go to a regular hospital in time.