Data from a new study released by the Fred Hutchinson Cancer Research Center show that undergoing circumcision before first sexual intercourse can help reduce the risk of prostate cancer in men. The study, published online in Cancer, a peer-reviewed journal of the American Cancer Society, showed that circumcision reduces the risk of infections and inflammatory conditions that can lead to cancer. Infections are often considered a cause of cancer, and researchers found that sexually transmitted infections contribute to the development of prostate cancer, and that circumcision reduces the incidence of sexually transmitted infections. Therefore, circumcision may reduce the incidence of certain types of prostate cancer. In this study, researchers analyzed the medical records of 3,399 men, 1,754 of whom had prostate cancer and the rest of whom were healthy. They found that men who were circumcised before their first sexual encounter had a 15 percent lower risk of developing prostate cancer than those who were not. This risk was reduced by circumcision in both benign and malignant prostate cancer patients: men who were circumcised before their first sexual encounter had an 18% lower risk of malignant prostate cancer and a 12% lower risk of benign prostate tumors than those who were uncircumcised. Infections caused by sexual transmission can cause prostate cancer by providing a suitable environment for cancer cells through chronic inflammation, and there are other mechanisms. Circumcision can reduce the risk of prostate cancer by strengthening the internal foreskin and improving the moist environment under the foreskin that may help pathogens survive, thereby inhibiting sexually transmitted infections. ”The results of these analyses suggest that infection and inflammation are associated with the risk of developing prostate cancer in certain patients,” said Dr. Wright, assistant professor of urology at the University of Washington School of Medicine. “The biological mechanism by which circumcision reduces the risk of prostate cancer revealed by these data is unclear, so we need more in-depth studies to elucidate the link between them.” He added.