1, prepuce, foreskin is not easy to clean its secretions, easy to accumulate the formation of foreskin scale; 2, the humid environment breeding pathogenic bacteria growth led to inflammation of the glans foreskin; 3, prepuce foreskin mouth narrow often can cause foreskin embedded, swelling; 4, prepuce and foreskin can cause male sexual dysfunction, premature ejaculation; 5, to minors will affect the development of the penis; 6, prepuce can induce penile cancer; 7, can cause female reproductive system diseases: vaginitis, cervical cancer, etc.