Patients with diabetes who develop foot ulcers need to be assessed for the nature of the ulcer before treatment. If the ulcer is ischemic, emphasis should be placed on resolving lower extremity ischemia. Patients with mild to moderate ischemia can practice internal medicine; patients with severe lesions can undergo interventional therapy or angioplasty, and the ulcer can be treated locally after the blood supply of the foot is improved. The treatment of diabetic foot ulcers is facilitated by reasonable hypoglycemic, antihypertensive, lipid-regulating and antiplatelet therapies; at the same time, it is necessary to actively treat diabetic arterial lesions of the lower limbs; if diabetic foot ulcers are combined with infections, sensitive antibiotics can be selected for the treatment after clinician’s diagnosis. Thorough debridement is conducive to ulcer healing. Hydrogel debridement is usually more favorable to ulcer healing than gauze dressing, surgical debridement or maggot debridement. Hyperbaric oxygen therapy for foot ulcer wounds helps to improve inflammation and microcirculation in the wound. Patients with diabetic foot ulcers should be seen by a medical professional.