About autologous fat transplantation, I receive a lot of questions from many users every day, involving various aspects, some issues can be explained in one sentence, some are not so clear, these issues that are not so clear, I will certainly find time to give you an explanation, it is a responsibility to me, because, with your trust! After autologous fat transplantation, will it “run” to other places? Before answering this question, please understand the next anatomical term: subcutaneous tissue! Subcutaneous tissue, also known as “subcutaneous adipose tissue”, is located below the dermis, with no obvious boundaries with the dermis, anatomically known as superficial fascia, clinically known as cellular tissue. Subcutaneous adipose tissue is a relatively loose layer of tissue, it is a natural cushion, can cushion external pressure, at the same time he is also a thermal insulator, can store energy. In addition to fat, subcutaneous adipose tissue is also rich in blood vessels, lymphatic vessels, nerves, sweat glands and hair follicles. The subcutaneous tissue is mesenchymal and consists mainly of fat cells, fibrous septa and blood vessels. In addition, there are lymphatic vessels, nerves, sweat glands, and hair follicles (papillae) in the subcutaneous tissue. The adipocytes are round or oval in shape, with an average diameter of about 94 microns, with larger ones reaching 120 microns. The adipocytes are clustered into fat lobules of varying sizes, which are bounded by fibrous intervals (fat lobule intervals). The subcutaneous tissue is rich in blood vessels, and small arteries branching from the lobular septa form capillaries that extend into the fat lobules and surround each adipocyte. The capillary basement membrane is in close contact with the adipocyte cell membrane and facilitates blood circulation and lipid transport. The subcutaneous tissue is distributed in the dermis and the muscle membrane, above the dermis and below the muscle membrane, forming the so-called fat layer, which accounts for 18% of body weight. Its thickness varies significantly depending on body surface area, age, gender, endocrine, nutrition and health status, etc. Generally speaking, women have more subcutaneous fat than men. After reading so much, three points should be clear: 1, the main components of subcutaneous tissue are fat cells, fibrous septum and blood vessels; 2, fat cells in the form of fat lobules exist in the fibrous septum; 3, each fat cell is surrounded by capillaries. The following two diagrams show that the main components of subcutaneous tissue are fat cells, fibrous septum and blood vessels, and fat cells exist in the form of fat lobules in the fibrous septum. Autologous fat transplantation is to suck excess subcutaneous fat cells from certain parts of the body itself, and then after the aspirated mixture is purified and processed to obtain purified fat particles, the intact granular fat cells are selected and then transplanted by injection to the parts of the body that need fat filling, such as breast and face, to achieve breast augmentation, facial contour improvement and facial rejuvenation. This is the general definition of autologous fat, and there is an important word in it, transplanting to the part that needs to be filled, which is very crucial and needs your special attention because the definition does not specify “where” it is transplanted to the part that needs to be filled. For the face, the specific location for transplantation/filling is mainly the subcutaneous tissues mentioned above; while for the breast, it is more complicated, which are the deep surface of pectoral muscle, pectoral muscle, between breast and pectoral muscle, deep subcutaneous layer and superficial subcutaneous layer, etc. Knowing the specific levels of autologous fat grafting/filling, it is convenient to understand whether the fat will “run” to other places after grafting. As shown in the diagram, due to the tissue structure, most of the transplanted fat is injected into the fat lobules in the face, which will hinder the movement of the transplanted fat due to the role of the lobular fiber interval. Therefore, from these two points, it can be seen that the fat transplanted to the new location is not likely to “run” to other places. In addition, the new blood vessels growing in are the biggest difference between autologous fat grafting and other inorganic grafts such as hyaluronic acid, and this is what determines the future of both …… In the chest, the fat transplanted into the subcutaneous tissue, like the face, cannot move. The fat transplanted into the deep surface of the pectoral muscle, the part of the fat tissue within the pectoral muscle, between the breast and the pectoral muscle, is even more “difficult to move” due to the anatomical structure of the starting and ending points of the muscle and the fusion of the boundaries of the deep and superficial tissues. Therefore, to sum up, the transplanted fat and the fat inherent in the body are “strictly controlled” by the human body, not “wherever you want to go”, and the fat transplanted/filled in the forehead or apple muscle that you see is “swollen” in the upper eyelids or cheeks after a few days. The essence of “swelling” is not that the transplanted fat has moved downward, but that the inflammatory and edematous fluid at the transplantation site has flowed downward!