After graduating from college, she joined a local company as a clerk and lived a carefree life like most young girls. However, at this time, fate played a big joke with her.
In June of this year, the young woman, the root of her left leg suddenly felt a little pain, can not make the strength, when walking, the heel of a landing, feel a tremor. Initially, she thought she had caught a cold and was fine after taking a break. I didn’t expect that a few days later, as the pain increased, I started to limp when I walked, and finally the pain was so bad that I couldn’t even walk 500 meters. He went to the local hospital for an MRI examination and was diagnosed with left femoral head necrosis. After visiting local and provincial hospitals, he came up with two options: one was to drill a hole in the leg to clean and treat the necrotic area. The second one is the common femoral head replacement. Both are invasive treatment methods, especially femoral head joint replacement, not only is the surgery expensive, causing greater economic pressure on the family, even if the surgery is successful, there are many patients left with legs of different lengths and other sequelae, resulting in a lifelong psychological shadow, for a young girl, either way is a huge blow. Once parents heard the news, anxious, overnight a lot of bubbles in the mouth, lost several pounds at once. After a detailed examination and medical history, the disease was further diagnosed. The day after the diagnosis was made, Xiaojuan underwent a combination of imaging-guided precision intervention and systemic conditioning therapy. “After the first outpatient treatment, I felt a large part of the pain relief, and after the treatment, I walked back to the ward independently from the outpatient treatment room.” Xiaojuan recalled. The immediate results gave Xiaojuan’s mother and daughter confidence in the treatment.
But progress was not always smooth. Halfway through the first course of treatment, the disease recurred. The pain seemed to return, and Xiaojuan’s mother’s and daughter’s eyes, which had been filled with hope, were dimmed and became worried again. As the treatment continued, the condition showed improvement. “Through my personal experience, I understood that there is an accumulative process in the treatment of any disease, and at the beginning of the second course of treatment, I felt that my condition was getting better day by day.” Xiaojuan happily talks about her treatment experience.
By the end of the second course of treatment, Xiaojuan’s hip joint Heris International score had improved from 76 points before admission to 91 points. “I can now go up and down the stairs and go for a walk for more than an hour without any discomfort, and I will find a new job as soon as I get home so that I don’t worry about my mother.” Before being discharged from the hospital, filial Xiaojuan told reporters. “As the inflammation in her body subsides, her condition will continue to improve.” Xiaojuan’s bedside doctor said. Hormones and alcoholism – two major causes of femoral head necrosis How did a young girl get this disease? Femoral head necrosis is known as the “undead cancer” and is a stubbornly painful disease. It is mainly caused by medical or non-medical hormone (food hormone pollution) application and alcohol abuse, it is estimated that there are 30 million patients with osteonecrosis of the femoral head worldwide and about 4 million in China, and the prevalence is on the rise. “In years of clinical practice, it has been shown that many male patients with femoral head necrosis are caused by long-term alcohol abuse, and Xiaojuan is a victim of improper medical hormone application.” Professor An Jianxiong told the reporter. Originally, a year ago, she had a cyst of 2-3 centimeters in diameter growing behind her left ear, and she went to a local hospital to have a minor surgery to remove it. In order to prevent post-operative wound infection, two tablets of amoxicillin were taken. But at this point, the next day, the body suddenly came out full of dense small rashes, and the whole body was unusually red and swollen. Her parents rushed her to the city hospital. This is a typical antibiotic allergy symptom. After a week of hormone shock therapy in the city hospital, Xiaojuan recovered and was discharged. After all this torment, it seemed that this “bad luck” had passed, but what Xiaojuan did not expect was that the following June, the above-mentioned scene occurred. “The two main sources of prevention of femoral head necrosis are the healthy and good living habits of the patients themselves and the careful use of hormones by medical workers.” Dr. Jianxiong An said. Ten years of relentless exploration to overcome medical challenges It has been 126 years since the discovery of osteonecrosis of the femoral head, and although there are various treatments, except for femoral head replacement, which is the equivalent of organ replacement, there has been a lack of evidence-based effective treatments, and most patients, especially in China, are reluctant to undergo surgery.
In the late 1990s, it was discovered that X-ray C-arm, X-ray computed tomography (CT) and ultrasound technology-guided interventions have gradually become popular in the West. One of the difficulties in the treatment of femoral head necrosis is that before the application of MRI technology, early diagnosis is very difficult, and once typical clinical symptoms and radiographic signs appear, the femoral head has already undergone irreversible collapse. The only effective treatment at this point is femoral head replacement.
In fact, inflammation, edema and ischemia are also the main pathological processes in the early and middle stages of femoral head necrosis, and most of these processes are reversible, in other words, it is possible to control the inflammatory process and achieve healing of the diseased femoral head before the collapse of femoral head necrosis. The data collected by MRI, CT and ultrasound technologies can be computerized and reconstructed in three dimensions, which in turn can help to design the precise site, angle and depth of the interventional puncture, so that the accurate injection of the appropriate dose of drugs into the lesion becomes a reality. For most painful diseases such as femoral head necrosis, Jianxiong An’s team has been able to perform precise interventional procedures in real time and in a dynamic and radiation-free manner. It has been found that these modern techniques can not only treat early diagnosis of femoral head necrosis, but have also established the theoretical basis and technical conditions for the treatment of the disease in terms of local pathophysiology. Recent studies have found that although local treatment of the femoral head is immediately effective, more measures are needed to maintain lasting results. He realized that a holistic approach to patient management was imperative. “To date, triple oxygen medicine has been practiced mainly in a few European countries, such as Germany, France and Italy, but has not been introduced into the United States and other leading countries of modern medicine. When medical triple oxygen technology was introduced into China at the beginning of this century, it was also resisted by some experts. However, after six years of continuous resistance, a few chance events changed the view of this technology: one is that the family of the manufacturer of the trioxgen generator has been using trioxgen for years for health care, and the other is that we have seen famous pain doctors in China using trioxgen themselves to lower blood lipids and reduce cold symptoms. In order to protect the patients, Dr. An Jianxiong insisted that he first received the trioxic autologous blood therapy before giving it to his patients. In the future, before promoting rectal triple oxygen and triple oxygen water therapy, Dr. An insisted to be the first to try it himself and to confirm that there were no side effects and complications before starting to use it on patients. After confirming the value of triple oxygen therapy in pain medicine, Dr. An established the Sino-German Carter Research Base for triple oxygen medicine with the German Carter Institute for Triple Oxygen Therapy to conduct in-depth research on the application of triple oxygen in pain medicine. From a philosophical point of view, many local lesions may be the local manifestation of abnormalities in the general environment. Although femoral head necrosis is manifested in the femoral head of the hip joint, among the four major causative factors, systemic hormone use, alcoholism and decompression sickness are all systemic factors, while only fracture and injury are local causative factors. This suggests that the development of femoral head necrosis is closely related to systemic health status. Research results have shown that a certain concentration of trioxane mixed with the patient’s own blood and then transfused back into the body can not only activate the anti-inflammatory and immune mechanisms in the body, but also effectively promote human metabolism. It was also found that rectal and intramuscular trioxane injections could achieve the same purpose. In view of the above considerations, Jianxiong An’s research group added trioxane autologous blood and rectal trioxane therapy to the local treatment of the diseased hip and femoral head, together with high-penetrating physical therapy, which not only accelerated the pain relief and hip function recovery of patients with femoral head necrosis. The results of the treatment of nearly 100 patients show that the complementary systemic modulation can make the efficacy of the precise therapy more durable.