Trigeminal neuralgia is a recurrent, transient, paroxysmal pain confined to the innervation area of the trigeminal nerve. Trigeminal neuralgia can be divided into two types: primary and secondary. The etiology and pathogenesis of primary trigeminal neuralgia are unknown. Secondary trigeminal neuralgia, also known as symptomatic trigeminal neuralgia, is often one of the clinical symptoms of a disease, such as by a tumor in the cerebellopontine angle and its adjacent areas. Cervical spondylosis is a general term for cervical osteoarthritis, proliferative cervical spondylitis, cervical nerve root syndrome, and cervical disc prolapse, which is a disorder based on degenerative pathological changes. It is a clinical syndrome that results in a series of dysfunctions due to long-term cervical spine strain, osteophytes, or disc prolapse and ligament thickening, resulting in compression of the cervical spinal cord, nerve roots or vertebral artery. It is caused by inflammation, trauma, and lesions in the branches of the trigeminal nerve. The diagnosis is usually clear with CT and MRI examinations. Clinical features The onset of pain is paroxysmal. Except for the fear of prolonged pain, the patient has no pain during the secondary attacks. When the attack occurs, it seems like a lightning-like stab. Pain attacks often present as sudden, paroxysmal episodes that can last 15 min or longer, and the frequency of attacks varies from a few times a day to several times a month. Treatment Preferred drug therapy, carbamazepine is the most commonly used drug, most patients can be relieved. However, pharmacological treatment requires attention to hepatic and renal impairment, hematopoietic system damage, etc. Nerve block treatment Local anesthetics and hormones are injected around the peripheral branches of the trigeminal nerve to play an anti-inflammatory and analgesic role, which can be used when drug treatment is not good, with a high recurrence rate. Radiofrequency thermocoagulation of the trigeminal ganglion (meningeal ganglion) Under the guidance of CT surveillance, radiofrequency electrocoagulation needles are inserted percutaneously into the meningeal ganglion and heated to 65-75℃, which can selectively destroy the nociceptive fibers of the trigeminal nerve, with a recent efficacy of more than 90%. It is suitable for patients with poor results of drug treatment, or who cannot tolerate drug treatment, or who have high side effects of drug treatment. Craniotomy The efficacy of craniotomy is exact, but the risk of surgery is greater than the previous ones, and there is a certain recurrence rate.