A temporal study on the onset of cardiovascular disease revealed that sudden heart attacks, such as myocardial infarction, have two peaks in a day: 1 to 2 hours after waking up and 10 to 12 hours thereafter, especially the first peak is more pronounced. In the past, it was found that hypertension also has this double-peak pattern, that is, the blood pressure rises at 7-9 am and 3-5 pm, so that stroke is also a high incidence in these two time periods. This pattern has important implications for the treatment and use of medication for coronary heart disease. Experts point out that if medication can be administered before the peak, it can undoubtedly reduce the risk of sudden onset of cardiovascular disease. Therefore, experts have proposed a biological rhythm health method, which believes that early rising and early going to bed, and a regular life, can effectively reduce this risk factor. At the same time, it can be combined with medication. The drugs usually taken for cardiovascular disease do not reach an effective therapeutic concentration until about 24 hours after they are taken. Therefore, once-a-day medications should be taken at 6 a.m., twice-a-day at 6 a.m. and 3 p.m., and thrice-a-day at 6 a.m., 12 p.m., and 5 p.m. This makes it possible to suppress the appearance of the double peak and reduce the risk of sudden heart attacks and strokes. According to this double-peak rule of coronary heart attack, the exercise of coronary heart disease patients also need to “set things right”, should change the traditional morning exercise to 9 pm exercise. Some people’s heart attack is due to improper morning exercise. On the one hand, exercise at 9 pm avoids the peak of the onset, on the other hand, it can also promote blood circulation and reduce the potential for morbidity. The exercise of patients with coronary heart disease should be moderate, after getting up in the morning can take a walk, do exercises, evening exercise can be based on their own situation to choose the appropriate project, time about 40 minutes, but must follow the principle of no obvious discomfort in the exercise and after exercise. Patients with more serious conditions, exercise must be carried out under the guidance of a doctor.