Abdominal pain of spinal origin is, as the name implies, a symptom of “abdominal pain” caused by a lesion in the spine. Due to the lack of understanding of this disease, patients are often referred to gastroenterology, abdominal surgery, gynecology, and pediatrics, but are not treated professionally, resulting in delays and poor outcomes. Age and gender The disease can develop from childhood to old age. It is particularly common in women and children, with both accounting for about two-thirds of the cases. The etiology of the disease is not fully understood, but it can be caused by prolonged poor sitting posture, strenuous exercise, and osteophytes [1]. Inflammation of the affected bone, surrounding tissues and nerves results in “abdominal pain”. In children, it may be caused by bony pain during the growth period. Clinical symptoms and signs Patients seek consultation with abdominal pain as the main complaint, and in mild cases, they only feel vague abdominal pain and their life and work are not affected; in severe cases, they may have acute onset with severe abdominal pain, accompanied by severe nausea, vomiting, inability to eat, painful appearance, and limited life and work. It is aggravated by activity. Physical examination: patients are mostly unable to point out a clear site of pain, the abdomen is flat and soft, without muscle tension and peritoneal irritation signs, there are no positive signs in all parts of the abdomen by light pressure, deep pressure above and below the umbilicus to the spine can produce severe pain, and similar signs can also be detected on the left or right side of the spine [2]. Compression can be felt from the subxiphoid process to the pubic symphysis, and pressure pain in a single vertebral body is rarely seen; individual patients may have abdominal aortic pressure pain of a similar nature, and some patients may have pressure points in the corresponding vertebral body in the low back (T10-L5). Laboratory and imaging tests Laboratory tests only detect mild leukocytosis, with no positive signs associated with abdominal pain. There were no positive signs on imaging. Diagnosis If the above symptoms and signs are met, and there are no other conflicting complaints and laboratory imaging evidence, abdominal pain of spinal origin can be considered. Treatment 1. Epidural block is preferred. Puncture in the upper interval of the painful vertebral body and administer 10 to 15 ml of 1% lidocaine, with the addition of steroids, which can be used in the majority of patients. 2, paravertebral injection, the same drug as above, in the corresponding vertebral body next to the injection, need more points, repeated, good healing. These two methods have a very low recurrence rate. 3, oral non-steroidal anti-inflammatory drugs, there is a certain degree of effectiveness. Easy to relapse. 4.Supportive therapy Severely ill patients should have appropriate medical support therapy, including caloric and electrolyte supplementation. Discussion Because this disease is rare clinically, and because many physicians lack knowledge of this disease, it is often misdiagnosed and mistreated [3]. It has been thought that the involvement of the posterior branch of the spinal nerve is the main cause of this disease [4], but the pressure pain in the spine is at the anterior edge of the vertebral body, and if the nerve root is involved, the anterior root should develop first, but no clinical cases of motor function involvement have been seen. Moreover, the site of abdominal pain and the corresponding spinal nerve distribution do not coincide, so it is presumed that most of them are still vertebral and local lesions. The nature is similar to that of spondylolisthesis. Both epidural block and paravertebral injection can inject drugs into the lesion to eliminate inflammation and make the “abdominal pain” symptoms disappear.