Radioactive particle-carrying esophageal stenting

  Recently, the Department of Thoracic Surgery, Department of Radiology and Department of Nuclear Medicine in our hospital successfully implanted a Ⅰ125 particle esophageal stent for a patient with esophageal cancer, which is the first case in our hospital and even in Qingdao, marking a new level in the treatment means and treatment level of esophageal cancer in our hospital.  The patient, 75 years old, had progressive dysphagia for more than one month, could only eat liquid food, and had a dysphagia score (Stooler grade) of III. The lesion was located in the middle esophagus and was a medium-differentiated squamous cell carcinoma. After searching a lot of domestic and foreign literature, Dr. Fan Xinglong, deputy chief of the Department of Thoracic Surgery, decided to implant a radioactive particle-carrying esophageal stent. With the strong support of Director Yin Zhiyi of Thoracic Surgery Department, Director of Radiology Department and Director of Nuclear Medicine Department, Deputy Chief Physician Fan Xinglong of Thoracic Surgery Department, Deputy Chief Physician Sun Yiyan of Radiology Department and Dr. Ding Yueyun of Nuclear Medicine Department cooperated with each other and applied TPS (Three-dimensional brachytherapy planning system) to calculate precisely the dose of I125 particles and accurately positioned them under X-ray guidance of Interventional Radiology Department. After the stent implantation, Mr. Li ate eight dumplings in one breath.  The application of memory alloy stent has become an important means of clinical palliative treatment of esophageal cancer and can effectively improve the survival quality of patients with advanced esophageal cancer, but the ordinary esophageal stent is only mechanical expansion and cannot fundamentally inhibit the growth of cancer cells. This technology loads I125 particles in a special particle sheath, which is firmly fixed, and its effective irradiation distance is 17mm, which will not cause harm to human health. effectively inhibit tumor growth and prolong the survival of patients.