Esophageal tissue injury caused by spontaneous or accidental swallowing of chemical corrosives, such as strong acids, strong bases, heavy metal salt solutions, etc. Strong acid burns mainly produce tissue protein coagulation necrosis; strong base burns produce more serious tissue dissolution necrosis, which is easy to penetrate the tissue. The degree of burns and the nature of corrosive agents, concentration, quantity and contact dwell time are closely related. The degree of tissue damage is generally divided into three degrees: first degree injury lesion is limited to the superficial mucosa of the esophageal wall, the acute phase of esophageal mucosa congestion edema, epithelial detachment, while the muscle layer tissue spasm produces esophageal obstruction. The acute inflammatory reaction subsided 1-2 weeks after the injury, and the tissue became necrotic and detached, and the obstruction was reduced. The tissue is repaired 2-3 weeks after injury, and scarred esophageal strictures may not be left behind if treated properly. Second-degree injuries are deeper, reaching the superficial muscular layer, with early mucosal ulceration and scar stenosis after healing. Third-degree injury involves the entire esophagus, and involves the surrounding esophageal tissue, resulting in perforation of the esophageal wall and secondary mediastinitis. Immediately after swallowing the corrosive agent, it causes strong pain in the mouth and behind the sternum, producing reflex vomiting, followed by dysphagia, febrile reaction, and in severe cases, systemic toxic symptoms such as hyperthermic coma. After the disease stabilizes, barium X-ray examination can observe the site and degree of esophageal stricture and the dilatation of the esophagus proximal to the stricture. Esophagoscopy can determine the site and degree of stricture, the condition of mucosal damage, and the presence of ulcers and foreign bodies, but the distal end of the first burned stricture cannot be visualized. Treatment of esophageal chemical burns is a complex issue, early first aid measures compete for time to abort the injury, after the occurrence of accidental ingestion first rinse the mouth with warm water, take protein water and vegetable oil, aluminum hydroxide gel to neutralize and dilute the concentration of corrosive agent, determine strong acid injury, take weak alkali, soapy water, determine strong alkali injury take weak acid, vinegar, fruit meter, etc., to protect the esophageal mucosa. early stage of I degree burns apply antibiotics and hormone The early stage of I degree burns should be treated with antibiotics and hormones, prednisone 20mg Q8h for 5 days and then gradually reduced. 48 hours later, esophageal dilatation can be considered and those who can eat should eat as soon as possible. II degree and III degree burns should be fasted to prevent perforation and high nutritional support therapy should be given intravenously. Early suspected perforation should be investigated by emergency surgery, and if necessary, the esophagus and stomach should be resected and the colon should be used as a substitute for the esophagus and stomach, but if there are no suspicious symptoms of perforation, conservative treatment is feasible. If esophageal stricture occurs 3-6 weeks after injury, esophagoscopic dilatation is feasible. In case of late long esophageal stricture or failure of dilatation, surgical treatment is required. Local resection can be chosen according to the stricture status, and gastric or colonic substitution esophageal anastomosis can be performed. If scar resection is difficult, bypass surgery can be performed with jejunum or colon instead of esophagus. Our department can also solve the problem of esophageal stricture by self-help esophageal dilatation technique, which has achieved good results.