Diabetic nephropathy can be slowed down after standardized treatment by professional doctors, which can improve the prognosis, and often has a poor prognosis if not treated actively in accordance with medical advice. Factors affecting the prognosis of patients with diabetic nephropathy mainly include the type of diabetes, the degree of proteinuria, renal function and extra-renal cardiovascular and cerebrovascular comorbidities such as the severity of the lesion.The process of renal damage in type 2 diabetes mellitus is basically similar to that of type 1 diabetes mellitus, except that hypertension occurs earlier, the incidence is higher, and there are many other complications. Patients with diabetic nephropathy should go to the endocrinology department of regular hospitals in a timely manner, and follow the doctor’s instructions to standardize the treatment, so as not to delay the condition and cause serious consequences.