The medicines for treating Helicobacter pylori include one proton pump inhibitor, one bismuth agent, and two antibiotics, i.e., one proton pump inhibitor + one bismuth agent + two antimicrobial medicines are used in combination. 1. Proton pump inhibitor: to inhibit the secretion of gastric acid, inhibit gastric acid secretion is strong and long-lasting, commonly used drugs include omeprazole capsules, rabeprazole capsules, pantoprazole tablets, epprazole and so on. 2. Bismuth: protect gastric mucosa, inhibit Helicobacter pylori, etc. Commonly used drugs include colloidal bismuth pectin capsules, bismuth citrate potassium tablets and so on. 3. Antibiotics: mainly have killing effect on H. pylori, the most commonly used drugs are clarithromycin capsule, amoxicillin capsule, levofloxacin, metronidazole, tetracycline, etc.. The drugs of H. pylori quadruple therapy should be taken regularly for 10-14 days, and the breath test should be rechecked after 1 month of discontinuation. People with H. pylori infection should follow the doctor’s advice on whether they need treatment and the use of related medications.