There are many clinical factors that cause women to not have menstruation, mainly divided into physiological factors and pathological factors. 1, first of all, physiological factors, if women of childbearing age have delayed menstruation and do not come, the first thing to consider is the possibility of pregnancy. 2, is due to pathological factors that cause women to have no menstruation, in the clinical more common is endocrine disorders, such as stressful life, frequent business trips, abroad, overwork, anger, cold, etc., may lead to endocrine disorders caused by menstruation. 3, if women over 45 years old do not have menstruation, and accompanied by sweating, insomnia, insomnia. If a woman over 45 years old does not get her period, accompanied by sweating, insomnia and hot flashes, it may be caused by the decline of ovarian function. The above situations should be treated promptly by a doctor to clarify the cause.