Patient, male, 37 years old. Self-reported epigastric pain, irregular episodes, lasting from a few minutes to more than 20 minutes, outside the hospital with gastritis given antacids and gastrointestinal dynamics of the drug treatment, did not see significant improvement. In March this year, at night, the epigastric pain worsened, with persistent severe pain and profuse sweating. She came to our hospital with normal electrocardiogram and was given acid-suppressing and analgesic treatments for acute abdomen, which relieved her pain. On the following day, the ECG was repeated with no significant changes. She came to the cardiology department and was admitted for consideration of coronary artery disease. After admission, there was no significant change in the electrocardiogram, and after adequate preoperative preparation, coronary angiography was performed: the middle portion of the left rotary branch of the coronary artery was completely occluded, and intervention was performed with the implantation of a stent. After follow-up, the current situation is better, epigastric pain did not recur. Tips: 1, electrocardiogram diagnosis of coronary heart disease has limitations, electrocardiogram normal can not exclude coronary heart disease; 2, young people with coronary heart disease is not rare, clinical encounter labor chest tightness or chest pain, to consider the diagnosis of coronary heart disease, and relevant examinations; 3, young people should avoid alcohol abuse, overwork, etc., chest tightness, chest pain and other discomforts, should be timely medical examination; 4, 80% of the cardiovascular disease with 80% of cardiovascular disease is related to poor lifestyle such as smoking, unhealthy diet and physical inactivity, etc. Quitting smoking can reduce the risk of heart attack by 50%.