Vulvar cramping is a symptom of a heavy sensation in the vulva due to vulvar smooth muscle tumors or vaginal inflammation. The principle of treatment for vulvar smooth muscle tumor is local excision of tipped fibroids or removal of deep fibroids. The prevention of vaginal inflammation is to abandon antibiotic abuse, wash underwear separately, avoid over-cleaning, pay attention to care during pregnancy, be wary of washing machines, and pay attention to hygiene in public places. Patients with vulvovaginal cramps can be diagnosed by their own symptoms, but they need to be differentiated from the following diseases. Differential diagnosis of vulvovaginal cramps: 1. Non-specific vaginitis: smear of secretions and microscopic examination with Gram stain can find common pathogens without the presence of mycobacteria or trichomonas. 2. Mycotic vaginitis: smear of the secretion, Gram stain, and microscopic examination may reveal clusters of Gram-positive ovoid spores, or pseudomycorrhizal filaments connected with germ cells in a chain or branched form.