Middle-aged and elderly people (especially those with a long history of smoking) who usually feel cold legs and feet, fear of cold, often feel sore and swollen calves after walking a certain distance, or soreness, and can walk for a while after stopping to rest, but after walking for a short time, they have to rest again (this is intermittent claudication), these manifestations may indicate that you are suffering from – -Lower extremity atherosclerosis occlusive disease. Many people do not understand this disease, and do not know how to treat this disease, or even think that it is a lumbar disc herniation, some patients because of improper treatment, fell skin ulceration, gangrene, and even limb necrosis and other serious complications, and even delayed the disease, and eventually had to amputate the limb. Lower extremity atherosclerosis is a manifestation of systemic atherosclerosis in the lower extremities. The plaque caused by atherosclerosis attaches to the arterial wall and protrudes into the arterial lumen, and as the plaque continues to expand and secondary thrombosis forms, the artery becomes narrow, the blood flow slows down and the blood flow decreases. When the stenosis reaches a certain level and even forms lumen occlusion, a series of symptoms including coldness and numbness in the lower limbs, leg muscle spasm, and soreness after exercise or even at rest are caused by insufficient blood supply. In the later stages of the disease, the artery may even evolve from sclerosis and stenosis to complete occlusion, when the limb is in a state of extreme ischemia even at rest, resulting in severe pain in the nerve endings called “resting pain”, especially at night when the temperature is low. At the same time, the skin and muscle tissues gradually lose their vitality due to ischemia, and eventually the affected foot, especially the toe, will become ulcerated or blackened and gangrenous, and the recurrent infection of the necrotic area is often uncontrollable with general drugs, resulting in the so-called “old rotten feet”. Interventional treatment of arteries in the lower extremities is minimally invasive, simple, effective and repeatable, with small incisions. In my clinical work, I often see some patients with lower limb atherosclerosis occlusive disease being misdiagnosed for a long time as general back and leg pain or calcium deficiency, and finally the affected limb has to be amputated due to severe pain and necrosis, which seriously affects the quality of life; I deeply feel the need to remind people, especially middle-aged and elderly people, to pay attention to lower limb atherosclerosis.