The treatment drugs for chronic erosive gastritis with HP positivity are omeprazole, metronidazole, bismuth pectin and so on. HP generally refers to Helicobacter pylori, patients with chronic erosive gastritis with positive Helicobacter pylori need to be treated with quadruple therapy, such as two antibiotics combined with proton pump inhibitors, bismuth treatment, such as metronidazole, amoxicillin combined with omeprazole, colloidal bismuth pectin. In addition, chronic erosive gastritis with Helicobacter pylori positivity can also use gastric mucosal protective agents such as magnesium aluminum carbonate, with abdominal distension, early satiety and other symptoms can be used to promote gastric dynamics such as domperidone treatment. Patients diagnosed with chronic erosive gastritis with H. pylori positive should actively cooperate with doctors for treatment.