There is no clear research result to show how long the patients with hyperthyroidism and type 2 diabetes can live, if the patients with hyperthyroidism and type 2 diabetes through standardized treatment may not even affect the survival period, if not standardized treatment caused by hyperthyroidism crisis, cardiovascular disease and other serious complications, then the patient’s survival period may be shortened. Patients with hyperthyroidism and type 2 diabetes mellitus should actively cooperate with the doctor’s treatment, follow the doctor’s instructions to take oral methimazole, propylthiouracil and other antithyroid drugs, the use of metformin, acarbose and other hypoglycemic drugs or injectable insulin therapy, the thyroid hormone levels, blood glucose control in a reasonable range of the prognosis is better, and even do not affect the survival of the patient. However, if thyroid hormone levels or blood glucose are not controlled properly without standardized treatment, thyroid crisis, diabetic nephropathy, diabetic cardiovascular disease and other serious complications may be induced, and the patient’s survival may be shortened, or even life-threatening. Patients diagnosed with hyperthyroidism with type 2 diabetes mellitus should actively cooperate with their doctors for treatment and maintain a healthy lifestyle, which will help improve the prognosis.