Hypogonadism is a relatively common condition. Hypogonadotropic hypogonadism (IHH) is a disease that occurs in the hypothalamus. Due to congenital abnormalities in the hypothalamus, which is the “commander” of endocrine hormone secretion in the body, it cannot correctly issue orders for the testes to develop and secrete androgens. As a result, people in their twenties still have testicles and penis like young children, no pubic hair, beard and other male characteristics, no normal sex life after marriage, no fertility, and if accompanied by smell disorder, it is also called Kalman’s syndrome. Long-term lack of androgens in the body also leads to osteoporosis, diabetes and cardiovascular disease, which endanger health and affect life expectancy. Most of the patients are male, their chromosomes and other endocrine functions are normal, their appearance is normal or even taller than normal, but androgen deficiency makes them lack strong muscles and strength, making them outwardly strong. Most of the patients do not receive good guidance and treatment for various reasons, and they have difficulty in talking about their “difference”, and they have low self-esteem and confusion, and do not know where to go. In fact, Kalman syndrome can become a real man through timely and appropriate treatment, and with some special treatment, it is also possible to have fertility. The main objectives of treatment for men with IHH are: 1) to restore sexual function, improve libido, and enhance the quality and enjoyment of sexual life; 2) to promote and maintain the development of secondary sexual characteristics; 3) to increase bone density and prevent osteoporosis; 4) to improve adult growth hormone deficiency; 5) to reduce the risk of cardiovascular events; 6) to restore fertility. The treatments are hormone replacement methods, including gonadotropin-releasing hormone pulse pump (GnRH pulse pump, also known as growth pump) pulse therapy, gonadotropin therapy, and sex hormone replacement. Among these treatments, the growth pump is the most ideal and physiologically appropriate method for treating this disease.