Follicular keratosis is an autosomal dominant genetic keratinization abnormal disease, which cannot be cured, but can be effectively improved by controlling the symptoms, and the relief methods taken are as follows: 1, daily skin care: patients with mild disease do not need treatment, or can use skin moisturizers and lubricants topically according to specific conditions to improve the symptoms of skin keratinization and dryness, and pay attention to the cleanliness and hygiene of the lesion area to prevent infection. Studies have shown that sunlight can lead to aggravation of follicular keratosis symptoms, so patients should do a good job of sun protection in life and try to avoid sunlight; 2, drug treatment: local use of retinoic acid preparations, severe cases can retinoic acid drugs, such as isotretinoin, Avia, etc., with anti-keratosis effect. In order to prevent and control infection, antibiotic treatment can also be used as appropriate, such as macrolides, tetracyclines, etc., but be aware of the need to be guided by a doctor to use drugs, because some drugs are prohibited for pregnant women, children and other groups, unauthorized use will cause adverse effects; 3, surgical treatment: for those who have limited, persistent lesions and hypertrophic lesions, grinding and direct surgical excision can be considered; 4, other Treatment: If the patient has a generalized lesion with greasy crust and bad odor or secondary infection, use neomycin solution for external washing followed by topical application of ichthyolite ointment for treatment. If patients have palmoplantar keratosis, they can use Chinese herbal medicine soak, which can soften and activate the blood and other effects.