There are many reasons for non-pregnancy, which may be summarized in dozens of ways. However, overall 40% of the causes are female, 40% are male, and 20% are mutual. There are many times when the cause is not found. The first step in finding the cause of infertility is the male examination. Semen analysis is simple, painless and non-invasive, and only requires 5-7 days without intercourse to remove the semen for a laboratory test, and the female partner is examined after the male examination is free of abnormalities, because the female examination is more complicated. Female examination includes: reproductive system examination, whole body examination, gynecological endocrine examination, etc. These examinations can reveal the causes of infertility, such as: reproductive organ abnormalities: unicornuate uterus, bicornuate uterus, septal uterus; reproductive organ diseases: tubal obstruction, uterine fibroids, endometriosis, etc.; systemic diseases: hyperthyroidism, diabetes mellitus, hypertension, anemia, etc.; gynecological endocrine abnormalities that cause infertility are more common, and polycystic ovary syndrome is a very common disease that causes infertility in recent years. Polycystic ovary syndrome is a very common disease causing infertility in recent years, and also amenorrhea and lactation syndrome. The treatment of infertility varies from person to person, with different treatment methods for different causes, such as surgery for organ malformation, reproductive tumors and tubal obstruction, medication for systemic diseases such as hyperthyroidism and anemia, and female hormonal medication for endocrine-induced infertility such as polycystic ovary syndrome. Many infertility cases are artificially caused. Many young people get pregnant without getting married and have abortions again and again, causing irreversible damage to the uterus and reproductive system, leading to infertility. Some people are impatient, anxious and angry leading to endocrine disruption, which affects pregnancy. Unstable life, frequent business trips from south to north, and no stable rest time throughout the year also do not make it easy to get pregnant. High work pressure and mental tension are also causes of infertility. Men who smoke and drink can also affect the quality of semen and cause infertility. In short, there are various causes of infertility, so patience is needed to check one by one and find a clear cause for the need for targeted treatment. Do not look in the east and west, Chinese doctors look at western doctors look at, spend a lot of money, no clear results. The possibility of curing infertility is decreasing with age.