Usually, patients can see the effect in about 30-60 minutes after using the fever suppositories. The main ingredient of antipyretic suppositories is acetaminophen, which has antipyretic and analgesic effects. This drug is absorbed through the mucous membrane of the large intestine to achieve antipyretic effect, avoiding the pain due to oral medication, intramuscular injection or intravenous injection. The common adverse reactions of patients are occasional rash, urticaria and other allergic reaction symptoms, long-term use of a large number of drugs may lead to abnormal liver and kidney function, so fever suppositories are generally used for no more than 3 days in a row, and should be used with caution in patients with liver and kidney insufficiency. In addition, patients must stop using it immediately when rash, urticaria and other allergic reaction symptoms appear. In conclusion, fever suppositories must be used under the guidance of a clinician, and patients are prohibited from taking other drugs containing antipyretic and analgesic ingredients to prevent adverse drug reactions; in addition, they can also drink more water during the medication period, and they must go to the community hospital or the infection department of a regular hospital promptly if their fever symptoms are not relieved for 3 consecutive days.