Diabetic patients inexplicably pus bubbles on the leg need to clarify the etiology, such as bacterial infection need to actively control blood sugar, under the guidance of the doctor using cephalosporin, metronidazole and other anti-infective treatment, if necessary, incision and drainage. Diabetic blood sugar control is not good in the case is easy to complicate a variety of infections, patients with pus bubbles on the leg, suggesting that may be bacterial infection, need to actively control blood sugar, under the guidance of the doctor using cephalosporin, metronidazole and other anti-infective treatment, if necessary, incision and drainage. There are many reasons for the appearance of pus bubbles in diabetic patients, it is recommended to consult a doctor in a timely manner, under the guidance of the doctor’s examination and treatment.