In recent years, with the continuous development of plastic surgery techniques, large post-burn, scald or chemical burn scars can be effectively treated. However, there are still some obvious superficial or atrophic scars after surgery, such as the surgical scar between the expanded skin and the normal skin after facial expander implantation, and the “patch-like” scar and pigmentation difference between the transplanted skin and the surrounding normal skin after autologous skin slice transplantation. In addition, more common are superficial scarring and pigment differences left behind by patients with superficial burns, scalds, or chemical burns, which are not clinically recommended for surgery or are not treated by the patients themselves. With the increasing concern for appearance, traditional treatment methods and efficacy are no longer sufficient to meet the needs of the population. The clinical application of fractional laser and microplasma treatment is a milestone in the treatment of keloid scars, both of which can produce microthermal damage areas either deeply or superficially, and induce the dermal collagen to enter into a “dissolution-regeneration” cycle, and finally the dermal collagen is reorganized, thus flattening the uneven scars. Furthermore, fractional laser and microplasma treatments can cause superficial skin exfoliation, physically destroying the epidermal “pigmentation” directly to improve the pigmentation difference between the scar and the surrounding tissue.