Adults with a fever of 39 ℃ or higher are considered hyperthermic and should be treated with timely cooling, including physical cooling and medication, in order to alleviate the patient’s pain and prevent the occurrence of convulsions or other adverse consequences. For those who have a history of febrile convulsions or who are irritable, sedative drugs should be given along with cooling. If the fever persists, it is recommended to consult a doctor. First, physical cooling patients with high fever need to choose the whole body cold therapy, can be used ice packs, ethanol swab bath way, to achieve the purpose of cooling. Second, drug therapy, mainly taking non-steroidal anti-inflammatory drugs, often using aspirin, acetaminophen and ibuprofen, etc., the interval of 4-6 hours can be repeated once, no more than 4 times a day with the drug. When using drugs to lower the temperature, attention should be paid to the dose of drugs, especially for the plain weak and cardiovascular disease, should be prevented from the phenomenon of collapse or shock. If the patient clearly has the condition of white blood cell reduction, the patient should not take ibuprofen suspension or acetaminophen suspension for antipyretic treatment, otherwise it will further cause the reduction of white blood cells. Third, clinical care Encourage patients to drink more water, to 3000ml per day is appropriate, in order to supplement the high fever consumption of a large amount of water, and promote the discharge of toxins and metabolites.