Often parents come to the ophthalmology department with their babies who have a red cloud on their face, “Doctor, after we finished seeing the dermatology department, they said that they would like to see you to check their eyes. The parents are worried about what kind of disease it is, and I will introduce it to you below. Sturge-Weber syndrome (sturge-webersy ndrome, SWS), i.e. cerebral trigeminal hemangiomatosis, also known as craniofacial hemangiomatosis, is a rare congenital neurocutaneous syndrome. There are no gender or racial differences, and the prevalence is 0.002% or less. This disorder primarily damages the skin, nerves, and eyes, presenting with congenital unilateral grape-colored nevus or flame-colored nevus of the face, calcification of the intracranial gyrus, intractable epilepsy, developmental and mental retardation, decreased learning ability, contralateral mild hemiparesis, hemiplegia, hemiplegia, ipsilateral hemianopsia, glaucoma, and other complications. Abnormal manifestations often begin at birth or in childhood and continue throughout life. According to different clinical symptoms, they can be divided into 3 types: 1. Facial hemangioma (nevus) and meningeal hemangioma: glaucoma may be present, often accompanied by convulsions and electroencephalogram abnormalities. There are typical manifestations of intracranial hemangioma imaging or histologic examination, which is typical of SWS. 2. Facial vascular nevus: without intracranial lesions, but with glaucoma. 3, No facial vascular nevus, only soft meningeal hemangioma, often without glaucoma. Recently, a fourth type has been proposed, which is a combination of other conditions, such as tuberous sclerosis, on top of SWS. It often begins at birth or in childhood and lasts for life. Because hemangiomas on the face are the first thing parents notice as a problem, they are often the first to be seen in dermatology, and dermatologists usually tell their patients to go to ophthalmology to rule out glaucoma and choroidal hemangiomas, and neurology to check for intracranial hemangiomas. Visual impairment is not a characteristic feature of the disease at birth, but as the brain develops and grows significant visual impairment can occur. 50%-70% of patients have glaucoma, most often in the later stages of life, which requires diagnostic attention and appropriate medication. Because the main brain lesion in Sturge-Weber syndrome is located in the occipital lobe, ipsilateral hemianopsia is common and often occurs at the same time as hemiparesis. Some patients may present with scleral hemangiomas, choroidal damage in the nevus, iris defects, and retinal pigmentation. The eye is usually a manifestation of congenital glaucoma: enlarged, grayish, photophobic, and tearing symptoms, or it may simply be a hemangioma of the fundus. It is necessary to go to the ophthalmology department to measure the intraocular pressure, corneal diameter, eye axis, to check whether there is a choroidal hemangioma in the fundus, and whether there is atrophy of the optic nerve. Treatment: 1. Treatment of facial hemangioma (nevus) Because hemangioma has self-regression, many scholars believe that most hemangiomas do not need any treatment or only need to meet the cosmetic needs of restoration. Superficial hemangioma or nevus of the head and face are more often treated with laser therapy. 94% of facial vascular nevus can be treated with this method. Deep hemangiomas that cause facial deformities can be surgically removed. 2, the treatment of epilepsy frequent seizures of epilepsy need long-term use of anti-epileptic drugs to reduce brain damage. Surgery can be considered in cases where medications do not control epilepsy well, but there is more debate about the timing of surgery. 3.Treatment of glaucoma caused by SWS is routinely treated with symptomatic treatment, first of all, medication, and with the improvement of surgical technology, surgery can also be taken. Endoscopic anterior chamber angulotomy, trabeculotomy, and ciliary body photocoagulation are effective procedures for the treatment of this congenital glaucoma. The aim of all these treatments is to control the intraocular pressure, minimize the damage to the optic nerve and preserve vision.