Cirrhosis is a pathological stage characterized by various factors to chronic inflammation of the liver, diffuse fibrosis, pseudobulbar, regenerative nodules and vascular proliferation inside and outside the liver, with no chronic changes in the compensated phase and clinical features of portal hypertension and hepatic decompensation in the decompensated phase. Commonly there are always the following causes: 1, viral hepatitis is a common cause in China (accounting for 60%-80%), of which hepatitis B is the most common, followed by hepatitis C, hepatitis A and hepatitis E acute liver injury, generally does not turn chronic; 2, chronic alcoholism is the most common cause in Europe and the United States (accounting for 50%-90%), in China about 15%, in recent years, China’s alcoholic liver has a significant increase 3, biliary stasis any cause of intra- and extrahepatic bile duct obstruction, sustained biliary stasis, can develop into biliary cirrhosis; 4, circulatory disorders hepatic vein or inferior vena cava obstruction syndrome, chronic cardiac insufficiency, constrictive pericarditis, resulting in long-term liver stasis, hepatocyte degeneration and fibrosis, and eventually develop into stasis cirrhosis; 5, parasitic infection schistosome eggs by the liver macrophages evolved into fibroblasts, forming fibrous nodules, leading to portal cirrhosis; schistosome eggs are parasitized in the bile ducts inside and outside the liver, causing bile duct infarction and inflammation, gradually developing into cirrhosis; 6, genetic metabolic diseases liver bean nucleus degeneration (copper deposition), hemochromatosis (iron deposition), liver glycogen accumulation disease (sugar deposition), etc.; 7, drugs or chemical toxins caused by long-term exposure to carbon tetrachloride, phosphorus, arsenic, etc., or taking certain drugs 8, immune disorders autoimmune hepatitis, a variety of rheumatic diseases involving the liver can progress to cirrhosis; 9, nutritional disorders long-term malnutrition, a variety of digestive malabsorption, obesity, diabetes and other fatty liver, can develop into cirrhosis; 10, cryptogenic cirrhosis refers to those with unknown causes, accounting for about 5-10%.