There is no exact course of treatment prescribed for the treatment of high uric acid with sodium bicarbonate tablets, and the medication can be adjusted according to the patient’s uric acid base. High uric acid is caused by abnormal purine metabolism in the body, and sodium bicarbonate tablets can assist in uric acid-lowering therapy. As an adjunctive treatment for hyperuricemia, this drug can alkalize urine, increase the solubility of uric acid, promote uric acid excretion, and achieve the effect of lowering blood uric acid. Sodium bicarbonate tablets can be used for patients with mildly high blood uric acid and low uric acid alkalinity can promote uric acid excretion when used alone. In the process of use, if the effect of lowering uric acid is not good, patients are recommended to go to the rheumatology and immunology department of the hospital for systematic examination and treatment, and perhaps other uric acid-lowering drugs need to be added. Meanwhile, patients with high uric acid also need to pay attention to the adjustment of dietary structure. First of all, they should abstain from alcohol, especially beer, avoid eating foods containing high purine, such as seafood, and scientifically eat fruits, vegetables, milk, eggs and other foods, and drink more water appropriately to facilitate the excretion of blood uric acid from the kidneys. In addition, it should be noted that patients with anuria or oliguria, renal insufficiency, congestive heart failure, or edema caused by sodium retention should not take sodium bicarbonate tablets, and it is recommended to consult a specialist and follow the doctor’s instructions on the specific usage and contraindications.