There are many causes of chest tightness and shortness of breath, and different causes need to be treated with different drugs. First, if the chest tightness and shortness of breath are caused by coronary heart disease, you need to take bai aspirin, resupristatin calcium tablets, and then take drugs that nourish the heart muscle, such as trimetazidine hydrochloride tablets and ginseng heart capsules can be. Secondly, if the chest tightness and shortness of breath are caused by cardiac insufficiency, you can take half a tablet of digoxin and spironolactone, and then add a little diuretic as well as potassium supplementation treatment. Thirdly, if the chest tightness and shortness of breath are caused by cardiac neurosis, patients need to regulate their emotions, keep a happy mood, pay attention to rest, and also take drugs that nourish the heart muscle, such as trimetazidine hydrochloride tablets.